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Which inositol works better for PCOS? new study compares two supplements

NCT ID NCT07453680

Disease control Sponsor: Mst.Sumyara Khatun Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at two dietary supplements, myo-inositol and d-chiro-inositol, to see which one better improves insulin resistance in infertile women with PCOS. 80 women took one of the two supplements for three months. The goal was to see if one is not worse than the other at lowering insulin resistance.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
myo-inositol and d-chiro-inositol (dietary supplements)
What this could lead to
If one supplement proves better or equal, it could offer a simple, non-drug option to help manage insulin resistance in women with PCOS.
What could go wrong
This is a small, completed trial with only 80 participants. Results may not apply to all women with PCOS, and supplements are not regulated as strictly as drugs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Jun 2023

Finished

May 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed case of PCOS according to Rotterdam criteria * Primary or secondary infertility * Insulin resistance (HOMA-IR \>2) Exclusion Criteria: * Age less than 18 years and more than 35 years * BMI less than 18.5kg/ m² and more than 30 kg/ m² * Endocrine disorders (Diabetes mellitus, hypothyroidism, hyperprolactinemia) * Any contraindications to MI or DCI * Any insulin sensitizer (metformin or inositol) in the last three months

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Conditions

The condition(s) this trial relates to.

Insulin Resistance polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PCOS (polycystic ovary syndrome)

Contacts and locations

Locations

  • Bangladesh Medical University

    Dhaka, 1000, Bangladesh

More trials for these conditions

Other studies related to the condition(s) this trial covers.