Can tracking PCOS over time unlock better care?
NCT ID NCT07739940
First seen Jul 31, 2026 · Last updated Jul 31, 2026
Summary
This study aims to create a large, long-term research cohort of women with polycystic ovary syndrome (PCOS). By systematically collecting follow-up data, researchers hope to understand how the condition evolves across different life stages and identify key factors that influence disease progression. The goal is to improve risk-stratified management and long-term health outcomes for women with PCOS.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- This research could lead to better long-term management strategies for PCOS, potentially reducing risks of diabetes, heart disease, and pregnancy complications.
- What could go wrong
- As an observational cohort study, it cannot prove cause and effect. Long-term follow-up may face challenges with participant retention, and findings may not apply to all PCOS patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 420 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study will enroll patients diagnosed with Polycystic Ovary Syndrome (PCOS) according to the 2023 International Evidence-based Guidelines for the Assessment and Management of PCOS, as well as age- and BMI-matched healthy controls with regular menstrual cycles. Participants will be recruited from the outpatient clinics of Guangdong Women and Children Hospital. Eligible participants will be consecutively enrolled on a voluntary basis after signing informed consent. Baseline clinical data including hormonal, metabolic, and ultrasound parameters will be collected at enrollment. All participants will be followed longitudinally to assess pregnancy-related outcomes and long-term complications.
- Ages
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16 to 45 years
- Sex
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Female participants only
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
I. Diagnostic Criteria: 2023 International Evidence-based Guidelines for the Assessment and Management of Polycystic Ovary Syndrome II. Inclusion and Exclusion Criteria: 1. PCOS Group Inclusion Criteria: Meets the above PCOS diagnostic criteria; Voluntarily signs the informed consent form; Has complete baseline clinical data (including hormonal, metabolic, and ultrasound parameters). Exclusion Criteria: Other conditions causing hyperandrogenism or ovulatory dysfunction; Use of hormonal medications within 3 months; Concurrent severe cardiac, hepatic, or renal diseases; Mental disorders that preclude compliance with follow-up. 2. Control Group Inclusion Criteria: Age- and BMI-matched healthy females; Regular menstrual cycles (21-35 days); No clinical manifestations or biochemical evidence of hyperandrogenism.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Guangdong Women and Children Hospital
Guangzhou, China
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Other studies related to the condition(s) this trial covers.
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