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Piano lessons may keep aging brains sharp, new study hints

NCT ID NCT06721390

Symptom relief Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether 12 weeks of piano improvisation training can improve thinking skills and self-control in adults aged 60 and older, including those with mild cognitive impairment. Participants will either take piano improvisation lessons or listen to music with an instructor. Researchers will measure changes in cognitive activity and self-regulation to see if making music offers unique brain benefits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Piano improvisation training
What this could lead to
If it works, this could point toward a simple, enjoyable activity to help older adults stay mentally sharp.
What could go wrong
This is an early-stage study with no phase, so results may not be conclusive. The intervention is short (12 weeks) and may not produce lasting benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 238 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2024

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 60 and over * Living independently in the community * Sufficient visual and hearing acuity (age-related to normal hearing loss, with assistive devices) * Less than three years of formal music training (as indicated by private music lessons does not include group or ensemble classes) and not currently reading or engaging in music performance * English fluency rated fairly well to well * MoCA score of 22-30 or diagnosis of "mild cognitive impairment * Not currently taking psychoactive medications, antidepressants, or sleep medications that could adversely affect cognitive abilities. Exclusion Criteria: * Medical diagnosis of dementia (any etiology) * Inability to move the hands or use all 10 digits (extensive arthritis, neuropathy, missing digits) * Score \< 22 on MoCA * Current (but not prior) severe psychiatric disorder, serious medical condition (e.g., stroke, TIA) that would interfere with participation in the study * Poor English fluency * Musician or previously trained in jazz improvisation, more than three years of formal music instruction or training and/or currently engaged in musical performance * Plans to move out of the area within six months

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Cognitive aging Cognitive impairment Cognitive training Cognitively normal older adults Mild cognitive impairment

Contacts and locations

Locations

  • The study is taking place at community sites in San Francisco.

    San Francisco, California, 94110, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.