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Can a cream beat hand arthritis pain? new trial aims to find out

NCT ID NCT06966206

Symptom relief Sponsor: St. Joseph's Healthcare Hamilton Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether Multiprofen-CC cream, applied three times daily, reduces pain in adults with hand osteoarthritis. Forty-two participants will use both the active cream and a placebo for two weeks each, in random order. Researchers will measure pain, hand function, and side effects to see if the cream offers real relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Multiprofen-CC cream (a topical pain reliever)
What this could lead to
If it works, this could offer a new topical option to ease hand arthritis pain and improve hand function without strong pills.
What could go wrong
This is a small, early-phase trial with only 42 people. The cream may work no better than placebo, and results may not apply to everyone with hand arthritis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 42 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (18+) * Have been diagnosed with hand osteoarthritis according to American College of Rheumatology criteria * Experience pain and/or loss of function in one or both hands that interferes with daily life * Provide informed consent Exclusion Criteria: * Unable to consent * Unable or unwilling to follow study protocol * Known allergy or contraindication to any of the study drugs or their ingredients * Have open wounds/cuts and/or skin conditions on the hand area * Pregnant or breastfeeding * History of impaired kidney or liver function * Rheumatoid or other inflammatory arthropathy * Hand surgery within the past 6 months or planned within the study period. * Use daily opioids (other than short acting codeine) for a chronic pain condition other than hand arthritis

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Conditions

The condition(s) this trial relates to.

arthritic joint disease osteoarthritis osteoarthritis susceptibility 2

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hand osteoarthritis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • St. Joseph's Healthcare Hamilton

    RECRUITING

    Hamilton, Ontario, L8N4A6, Canada

More trials for these conditions

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