Can acupuncture outperform a fake procedure for arthritic hands?
NCT ID NCT05267093
First seen Sep 10, 2026 · Last updated Sep 11, 2026 · Updated 1 time
Summary
Researchers are testing whether acupuncture relieves pain and improves function in people with hand osteoarthritis. The trial enrolls 340 adults aged 18 to 80 who have had hand osteoarthritis for at least three months and have used anti-inflammatory drugs for it. Participants receive either real acupuncture or a sham procedure, and researchers compare how many in each group meet standard criteria for meaningful improvement.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- acupuncture
- What this could lead to
- If acupuncture outperforms the sham procedure, it could offer a drug-free option for easing hand osteoarthritis pain.
- What could go wrong
- Acupuncture may work no better than the sham procedure, and any benefit could come from expectation rather than the needles. Results from this single trial may not generalize to all patients with hand osteoarthritis.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 340 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2022
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed as hand OA according to the American College of Rheumatology (ACR) clinical classification criteria * History of hand OA for at least 3 months before enrollment and history of taking nonsteroidal anti-inflammatory drugs (NSAIDs) to treat hand OA * Aged 18-80 years * At least 40 mm in visual analog scale (VAS) on the average pain intensity of the dominant hand over the last 48 hours (patients applying NSAIDs at the screening have to have an increase in pain in the dominant hand of ≥ 20 mm after 1-week washout) * Posterior-anterior radiographs of the dominant hand shows Kellgren-Lawrence grade 1, 2, or 3 changes in symptomatic joints * Negative results in both rheumatoid factor and anticyclonic citrullinated peptide * Able to comply with the study protocol and understand the medical information forms * Voluntarily sign the informed consent Exclusion Criteria: * History or current evidence of secondary OA (due to causes other than a solely degenerative joint disease) or symptomatic OA at additional locations besides the hand(s) requiring treatment, or any painful syndrome of the upper limb which may interfere with evaluation of hand pain; * History of inflammatory arthritis (such as rheumatoid arthritis (RA) or psoriatic arthritis), hemochromatosis, metabolic, or neuropathic arthropathies; * History of trauma, dislocation or operation to the hand or arm in the previous 3 months; * Hand pain and stiffness due to tissue scarring or tendinitis; * Skin damage or serious skin disorders in the hands; * Intake of antidepressants, anticonvulsants, vascular or narcotics during the 10 days prior to beginning the study; * Oral, intramuscular, intra-articular or intravenous corticosteroids, or hyaluronic acid injection within 3 months preceding enrollment; * Serious uncontrolled medical conditions such as cancer, uncontrolled cardiovascular disorder, severe hepatic/renal insufficiency or coagulation disorder; * Known phobic to acupuncture or received acupuncture treatment within 4 weeks prior to enrollment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences Guang'anmen Hospital
RECRUITINGBeijing, China
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