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Repeated Skin-Release procedure may smooth old acne scars

NCT ID NCT02216864

Symptom relief Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This pilot study tests whether performing multiple subcision procedures over several visits can improve rolling acne scars. Rolling scars are depressed areas of skin caused by past acne. Subcision involves inserting a small blade under the skin to break up fibrous bands that tether the scar down. The study compares treated versus untreated sides of the face in adults aged 18 to 65 with bilateral rolling scars and no active acne.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
multiple subcision procedure
What this could lead to
If effective, this approach could offer a way to improve the appearance of rolling acne scars without drugs or lasers.
What could go wrong
This is a very small pilot study with only 5 participants, so results may not apply broadly. The procedure involves cutting under the skin and carries risks like bruising, infection, or uneven results.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

5 people

The number who actually took part.

Start date

Aug 2014

Finished

Jun 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18 to 65 2. Have bilateral rolling acne scars on each side of their face 3. No active or ongoing acne. 4. The subjects are in good health 5. The subject has the willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator. Exclusion Criteria: 1. Under 18 years of age 2. Pregnancy or Lactation 3. Subjects who are unable to understand the protocol or to give informed consent 4. Subjects with mental illness 5. Recent Accutane use in the past 6 months 6. Subjects prone to hypertrophic and keloidal scarring 7. Subjects reporting any blood diseases (HIV, Hepatitis, etc.) 8. Subjects reporting a history of Herpes (oral or genital)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acne scars

Contacts and locations

Locations

  • Northwestern University Feinberg School of Medicine, Department of Dermatology

    Chicago, Illinois, 60611, United States

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