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Engineered immune cells take aim at Hard-to-Treat cancers

NCT ID NCT06253520

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 26 times

Summary

This early-phase trial tests a personalized treatment for adults with metastatic solid tumors (like colorectal, lung, or breast cancer) that have a specific genetic change called KRAS. Doctors take a person's own white blood cells, modify them in a lab to better recognize and attack cancer cells, and return them to the patient along with a vaccine to boost their effect. The goal is to see if this combination is safe and can shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.