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Sickle cell Drug's inner workings revealed in new study

NCT ID NCT05675436

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 29 times

Summary

This study looks at how the drug mitapivat changes red blood cells in people with sickle cell disease. Researchers will measure oxygen levels and cell health using blood tests and a skin sensor. The goal is to understand how the drug works, not to test if it cures the disease. About 6 people already in a larger study will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

The condition(s) this trial relates to.

Hemoglobin SC Disease sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.