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Mind over ache: could meditation tame MS pain?

NCT ID NCT07741864

Symptom relief Sponsor: Hospital Universitario Virgen Macarena Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This trial tests whether a structured mindfulness program can reduce pain in adults with multiple sclerosis. Participants are randomly assigned to either the mindfulness group or an educational program, and their pain, fatigue, sleep, mood, and quality of life are tracked over several months. The goal is to see if mindfulness offers extra benefits beyond standard education for managing MS-related pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A group-based mindfulness program for pain management, including meditation, mindful yoga, and pain education, delivered over eight weekly sessions plus a retreat.
What this could lead to
If effective, this could offer a drug-free way to help people with multiple sclerosis manage chronic pain and improve their quality of life.
What could go wrong
The trial is relatively small and early, so results may not apply to everyone. Mindfulness may not reduce pain for all participants, and the benefits could be modest or short-lived.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 84 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 80 years. * Diagnosis of multiple sclerosis with an Expanded Disability Status Scale (EDSS) score between 1.0 and 7.0. * Presence of pain. * Ability to provide written informed consent. Exclusion Criteria: * Severe cognitive impairment. * Diagnosed psychiatric disorders (e.g., schizophrenia or personality disorders). * Participation in another non-pharmacological intervention specifically aimed at pain management. * If receiving stable pain medication, treatment must have been maintained for at least 4 months before enrollment. * Unwillingness to provide informed consent.

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Conditions

The condition(s) this trial relates to.

agnosia multiple sclerosis Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple sclerosis Pain Pain management

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hopsital Universitario Virgen Macarena

    Seville, Sevilla, 41009, Spain

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