Could a heart drug save babies with a rare birth defect?
NCT ID NCT02951130
First seen Nov 06, 2025 · Last updated May 21, 2026 · Updated 24 times
Summary
This study tested a drug called milrinone in 66 newborn babies with congenital diaphragmatic hernia (CDH), a condition where a hole in the diaphragm allows organs to move into the chest, making it hard for the lungs to develop and work. The goal was to see if milrinone could safely improve oxygen levels by helping the heart pump better and relaxing blood vessels in the lungs. While the drug is already used in some hospitals, this was the first randomized trial to check if it truly helps compared to a placebo.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Brown University, Women & Infants Hospital of Rhode Island
Providence, Rhode Island, 02905, United States
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Case Western Reserve University, Rainbow Babies and Children's Hospital
Cleveland, Ohio, 44106, United States
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Children's Hospital of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Children's Mercy
Kansas City, Missouri, 64108, United States
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Cincinnati Children's Medical Center
Cincinnati, Ohio, 45267, United States
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Columbia University
New York, New York, 10032, United States
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Duke University
Durham, North Carolina, 27710, United States
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Emory University
Atlanta, Georgia, 30303, United States
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RTI International
Durham, North Carolina, 27709, United States
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Research Institute at Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Stanford University
Palo Alto, California, 94304, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
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University of Iowa
Iowa City, Iowa, 52242, United States
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University of New Mexico
Albuquerque, New Mexico, 87131, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Rochester
Rochester, New York, 14642, United States
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University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
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University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, 75235, United States
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University of Utah
Salt Lake City, Utah, 84108, United States
Conditions
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