New hope for brain surgery pain: single dose methadone may beat standard care
NCT ID NCT06810336
First seen May 22, 2026 · Last updated Jun 18, 2026 · Updated 7 times
Summary
This study tests whether a single dose of methadone given during brain surgery can control pain and improve recovery better than the usual short-acting opioid remifentanil. About 40 adults having elective brain surgery will be randomly assigned to receive one of the two medicines. The goal is to see if methadone leads to less pain, less need for extra painkillers, and a better overall recovery in the first few days after surgery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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University of Virginia
RECRUITINGCharlottesville, Virginia, 22908-0710, United States
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