Metaverse therapy: could virtual cooking and escape rooms heal the brain?

NCT ID NCT07456475

Symptom relief Sponsor: Istituto per la Ricerca e l'Innovazione Biomedica Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a set of virtual reality exergames in the Metaverse to help people with neurological conditions like multiple sclerosis, Parkinson's disease, stroke, and traumatic brain injury improve their cognitive skills. 25 participants will try games like virtual cooking and escape rooms. The goal is to see if this approach is acceptable and usable, not yet to prove it works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: virtual reality exergames (TERSICORE digital platform)
What this could lead to: If it works, this could offer a fun, social way to boost thinking skills for people with brain disorders.
What could go wrong: This is a very small early study (25 people) focused on feasibility, not proof of benefit. The virtual reality may cause motion sickness or not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 25 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for patients: * Adult age: 18-85 years * Education: at least 5 years * Cognitive deficits at routine outpatient clinical neuropsychological assessment (at least one test with p.e. 0/1) in subjects with focal neurological insult - (post-Stroke, post-Cranial Trauma) * neurodegenerative disorders - (Multiple Sclerosis, Parkinson's, Mild Cognitive Impairment, AD-like) Exclusion criteria for patients: * Severe cognitive impairment MMSE \<22 * Presence of severe deficits in visual acuity, hearing perception, communication and severe dysmetria, such as to interfere with the administration of the activities proposed by TERSICORE * Presence of major psychiatric or neurological pathologies other than the inclusion criteria

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Brain Injuries, Traumatic multiple sclerosis nervous system disorder Parkinson disease stroke disorder traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple sclerosis Neurological disorder Parkinson disease Stroke Traumatic brain injury

Metaverse therapy: could virtual cooking and escape rooms heal the brain?

What the study statuses mean