What happens inside you after eating? new study maps nutrient processing
NCT ID NCT05784506
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study measured how the body handles different nutrients—sugar, protein, and fats—by giving 147 healthy adults various food tolerance tests. Researchers tracked changes in hormones and other substances in the blood to understand nutrient processing patterns. The goal is to learn how different foods affect metabolism, which could eventually help improve diets for people with conditions like obesity and diabetes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help design better diets for people with metabolic disorders like obesity and diabetes.
- What could go wrong
- This is an observational study that only measures short-term responses; it does not test a treatment or provide direct health benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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147 people
The number who actually took part.
- Started
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Sep 2023
- Finished
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Dec 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Those who agree to participate in the study and sign informed consent. 2. Age between 20 and 65 year. 3. Fasting plasma glucose \< 7.0mmol/l, and 2-hour postprandial plasma glucose \< 11.1mmol/l. 4. BMI \> 18 kg/m2. Exclusion Criteria: 1. History of diabetes. 2. Pregnant or lactating women. 3. The subjects had not received oral/systemic corticosteroids for 7 consecutive days during the last 6 months. 4. Subjects were taking medication known to affect glucose metabolism. 5. Subjects who take strong inhibitors of cytochrome P450 (CYP)3A4/5, for example, ketoconazole, azanaway, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ritonavir, saquinavir and telithromycin. 6. Patients with either of the following characteristics of severe hepatic disease: i. Two consecutive abnormal hepatic function results during recent four weeks, with ALT or AST three times the upper limit of the institutions normal reference ranges. ii. Hepatic excretion dysfunction (eg. hyperbilirubinemia) and/or synthesis dysfunction, or other decompensated liver disease. iii. Acute viral hepatitis, autoimmune hepatitis, and alcoholic hepatitis 7. Patients with moderate and severe renal impairment, and end-stage renal disease (serum creatinine \> 194.5 mmol/L, or serum potassium \> 5.5 mmol/L). 8. New York Heart Association (NYHA) functional class III or IV congestive heart failure. 9. History of acute or chronic pancreatitis. 10. History of gastrointestinal disorders: gastroenterostomy, enterectomy, ileus and intestinal ulcers. 11. Subjects with previously diagnosed malignancy within the past 5 years. 12. Any other reasons that the investigator considered inappropriate to participate in the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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First Affiliated Hospital, Nanjing Medical University
Nanjing, Jiangsu, 210029, China
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Other studies related to the condition(s) this trial covers.
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