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Can tiny injections ease jaw pain? new study says maybe

NCT ID NCT07630909

Symptom relief Sponsor: Future University in Egypt Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether mesotherapy — injecting anti-inflammatory medicine into the skin near the jaw — can help people with chronic jaw muscle pain. Twenty-two adults with myofascial pain syndrome received treatment over 4 weeks. Researchers measured pain levels and how wide they could open their mouths before and after treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

22 people

The number who actually took part.

Started

Sep 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. patients between 18 - 60 years. 2. Patients who had a Diagnosis of TMD, with chronic pain, muscle spasms, myofascial pain syndrome lasting at least 3 months, and challenges while chewing. 3. Patients who have difficulty opening their mouths, cases where conservative treatment methods (physical, medical, or appliances) have failed. 4. Patients who have Bruxism - Exclusion Criteria: 1. Systemic Diseases such as uncontrolled Diabetes, uncontrolled hypertension disorders of coagulation (hemophiliacs, undergoing therapy with anticoagulants or antiplatelet agents, and cancer patients undergoing chemotherapy. 2. Patients with a history of Muscular dystrophies, Myasthenia Gravis, Polymyositis, Rheumatoid arthritis, Hypothyroidism, and Sarcoidosis 3. Patients with active Infections around the injection site. 4. Females who are pregnant or breastfeeding are excluded. 5. A patient who had a history of severe mental health disorders or neurological conditions affecting pain perception or compliance. 6. Patients with allergies to the components used in mesotherapy.

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Conditions

The condition(s) this trial relates to.

myofascial pain syndrome temporomandibular joint disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Myofascial pain syndrome (MPS)

Contacts and locations

Locations

  • Faculty of Oral and Dental Medicine, Future University in Egypt

    New Cairo, Cairo Governorate, 4740011, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.