Knee repair surgery may delay arthritis
NCT ID NCT03037242
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows 55 people aged 18-65 who have a meniscus root tear and undergo a specific surgical repair called transtibial pullout. Researchers will track knee function and arthritis progression over time to see if the procedure works well and what factors might lead to poor results.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- transtibial pullout technique (surgical procedure)
- What this could lead to
- If successful, this could confirm that meniscus root repair effectively restores knee function and slows arthritis progression.
- What could go wrong
- This is an observational study with only 55 participants, so results may not apply to everyone. The surgery may fail or arthritis could still worsen.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 55 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2017
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Meniscus root avulsion tear (defined as meniscus posterior horn root avulsion or full thickness tear within 9 mm of the root attachment) 2. Age 18-65 3. Ligament injury with concomitant reconstruction is acceptable 4. Malalignment with corrective osteotomy is acceptable Exclusion Criteria: 1. Subchondral collapse on pre-op MRI 2. Extrusion greater than 3 mm 3. Intra-op Outerbridge grade 3 or greater chondromalacia 4. Intra-op poor quality meniscus tissue 5. Mal-alignment greater than 5 degrees without corrective osteotomy 6. Obesity with BMI over 40 7. Kellgren Lawrence \> grade 2 8. Worker's compensation status
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Columbia Orthopaedic Group
Columbia, Missouri, 65201, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Other studies related to the condition(s) this trial covers.
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