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New drug combo shows promise for Hard-to-Treat cancers

NCT ID NCT02734004

First seen Jan 05, 2026 · Last updated May 24, 2026 · Updated 20 times

Summary

This study is testing a combination of two drugs, MEDI4736 (which helps the immune system fight cancer) and olaparib (which targets cancer cells with DNA repair problems), in people with advanced solid tumors like ovarian, breast, lung, and stomach cancers. The goal is to see if the combination can shrink or control the tumors. About 264 participants are involved, and the study is currently active but not recruiting new patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Newnan, Georgia, 30265, United States

  • Research Site

    Towson, Maryland, 21204, United States

  • Research Site

    Boston, Massachusetts, 02114, United States

  • Research Site

    Detroit, Michigan, 48202, United States

  • Research Site

    St Louis, Missouri, 63110, United States

  • Research Site

    Hilliard, Ohio, 43026, United States

  • Research Site

    Philadelphia, Pennsylvania, 19104, United States

  • Research Site

    Bordeaux, 33076, France

  • Research Site

    Caen, 14076, France

  • Research Site

    Clermont-Ferrand, 63011, France

  • Research Site

    Dijon, 21079, France

  • Research Site

    Marseille, 13385, France

  • Research Site

    Nantes, 44202, France

  • Research Site

    Paris, 75014, France

  • Research Site

    Pierre Benit Cedex, 69495, France

  • Research Site

    Toulouse, 31059, France

  • Research Site

    Villejuif, 94805, France

  • Research Site

    Haifa, 91096, Israel

  • Research Site

    Jerusalem, 91031, Israel

  • Research Site

    Petah Tikva, 49100, Israel

  • Research Site

    Ramat Gan, 5265601, Israel

  • Research Site

    Tel Aviv, 6423906, Israel

  • Research Site

    Amsterdam, 1066 CX, Netherlands

  • Research Site

    Amsterdam, 1081 HV, Netherlands

  • Research Site

    Maastricht, 6229 HX, Netherlands

  • Research Site

    Nijmegen, 6525 GA, Netherlands

  • Research Site

    Rotterdam, 3075 EA, Netherlands

  • Research Site

    Utrecht, 3584 CX, Netherlands

  • Research Site

    Goyang-si, 10408, South Korea

  • Research Site

    Seongnam-si, 13620, South Korea

  • Research Site

    Seoul, 03080, South Korea

  • Research Site

    Seoul, 03722, South Korea

  • Research Site

    Seoul, 05505, South Korea

  • Research Site

    Seoul, 06273, South Korea

  • Research Site

    Seoul, 06591, South Korea

  • Research Site

    Seoul, 135-710, South Korea

  • Research Site

    Chur, CH-7000, Switzerland

  • Research Site

    Lausanne, 1011, Switzerland

  • Research Site

    Cambridge, CB2 0QQ, United Kingdom

  • Research Site

    Dundee, DD1 9SY, United Kingdom

  • Research Site

    Glasgow, G12 0YN, United Kingdom

  • Research Site

    Greater London, SW3 6JJ, United Kingdom

  • Research Site

    London, NW1 2PG, United Kingdom

  • Research Site

    London, SE1 9RY, United Kingdom

  • Research Site

    Manchester, M20 4BX, United Kingdom

  • Research Site

    Newcastle upon Tyne, NE7 7DN, United Kingdom

  • Research Site

    Sutton, SM2 5PT, United Kingdom

Conditions

Explore the condition pages connected to this study.