Does pot make you drink more? study investigates
NCT ID NCT02983773
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how smoking marijuana with different levels of THC affects alcohol cravings and drinking in people who are heavy drinkers and also use marijuana. 157 participants were given either a high-THC, moderate-THC, or placebo marijuana cigarette, then their alcohol cravings and drinking choices were measured. The goal was to understand the relationship between marijuana and alcohol use, not to test a treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- THC (tetrahydrocannabinol) in smoked marijuana cigarettes
- What this could lead to
- If successful, this could help understand how marijuana use influences alcohol cravings and drinking behavior, potentially informing future treatments for co-use.
- What could go wrong
- This is a small, early-stage lab study with 157 participants, not designed to test a treatment. Results may not apply to real-world settings or to people seeking treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
157 people
The number who actually took part.
- Started
-
Jan 2017
- Finished
-
Jul 2021
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
21 to 44 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 21 to 44 * English-speaking * marijuana smoking in past month * report of current heavy episodic (binge) drinking * in good physical health and weighing \< 250 lbs * zero breath alcohol at each visit Exclusion Criteria: * history of seizures * smoking \>20 tobacco cigarettes per day * positive pregnancy test * nursing * positive urine toxicology screen for drugs other than cannabis * interest to quit or receive treatment for marijuana or alcohol use * meeting criteria for a current affective disorder (depression, or mania, panic disorder, and having psychotic symptoms as assessed by the SCID)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Brown University
Providence, Rhode Island, 02912, United States
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