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New hope for Moms-to-Be: drug targets dangerous pregnancy itch

NCT ID NCT07389031

First seen Feb 05, 2026 · Last updated Jun 07, 2026 · Updated 20 times

Summary

This early-stage study tests a drug called maralixibat in 28 pregnant women with intrahepatic cholestasis of pregnancy (ICP), a liver condition that causes severe itching and high bile acids. The main goal is to see if the drug is safe and tolerable for both mother and baby. Researchers will also check if it helps reduce itching and lower bile acid levels.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Birmingham Womens and Childrens NHS Foundation Trust

    Birmingham, B15 2TG, United Kingdom

  • Guy's and St Thomas' NHS Foundation Trust

    London, SE 1 7EH, United Kingdom

Conditions

The condition(s) this trial relates to.

cholestasis intrahepatic cholestasis of pregnancy Pruritus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.