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Could gentle manual therapy unlock relief for chronic jaw pain?

NCT ID NCT06627855

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This trial tests whether a specific type of manual therapy, based on the Fascial Distortion Model, can reduce pain and improve function in people with temporomandibular disorders (TMD), which cause jaw, face, or neck pain. Participants are randomly assigned to receive either the real therapy or a sham (fake) version to see if the technique has a genuine effect. The study measures jaw and neck movement, pain levels, muscle performance, and quality of life before and after treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Manual therapy based on the Fascial Distortion Model (Typaldos Manual Therapy)
What this could lead to
If effective, this hands-on therapy could offer a drug-free way to reduce jaw pain, improve jaw and neck movement, and enhance quality of life for people with temporomandibular disorders.
What could go wrong
This is a small early-stage trial with only 30 participants, so results may not apply broadly. The therapy's benefit over sham treatment is uncertain, and individual responses may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 64 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Having temporomandibular joint complaints and being diagnosed with temporomandibular disorder according to the Diagnostic Criteria for Temporomandibular Disorders Axis I * Understand and be willing to answer assessment questions * A temporomandibular joint complaint for the last three months * Pain in the jaw, face or neck Exclusion Criteria: * Has a systemic disease (neurological, rheumatologic, oncologic, etc.) that may affect the temporomandibular joint, cervical spine and/or assessment * Any history of trauma that may have affected the cranio-cervico-facial region * Having undergone any surgical intervention in the cranio-cervico-facial region within the last six months * Receiving surgical treatment, medical treatment, splint therapy or physiotherapy for temporomandibular disorder in the last month * Radiotherapy in the head and neck region * Pregnancy or breastfeeding * Exercise therapy for craniocervical posture for the last month

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Karabük University

    RECRUITING

    Merkez, Karabük Province, 78050, Turkey (Türkiye)

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