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Can a simple massage help septic shock patients heal faster?

NCT ID NCT05874895

Symptom relief Sponsor: University Hospital Ostrava Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether manual lymphatic drainage, a gentle massage technique, is safe and feasible for patients recovering from septic shock. Researchers enrolled 24 adults in the ICU and compared those who received the massage plus usual care to those who received usual care alone. The goal was to see if the massage could help reduce organ failure and improve recovery without causing harm.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Manual lymphatic drainage (a gentle massage technique to move lymph fluid)
What this could lead to
If it works, this could offer a simple, non-drug way to help patients recover faster from septic shock and reduce organ failure.
What could go wrong
This is a very small pilot study with only 24 patients, so results are preliminary. The procedure may not improve outcomes or could interfere with standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

24 people

The number who actually took part.

Started

Jun 2023

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * diagnosis of septic shock at admission to ICU * sepsis or suspicion of sepsis * noradrenaline support required in order to maintain mean arterial pressure ≥ 65 mmHg * serum lactate ≥ 2 mmol/L Exclusion Criteria: * patients \<18 years of age * pregnant women with septic shock, in whom the pregnancy has been preserved * patients with a history of heart failure with NYHA (New York Heart Association) classification ≥ III * patients with a history of thromboembolic events * patients with septic shock transferred from another department/hospital, if the length of stay at the previous workplace exceeded 72 hours * patients with septic shock and an inauspicious prognosis, or in the phase of withdrawal of treatment * patients with uncontrolled infection * patients with septic shock who lack informed consent * patients with septic shock, in whom the SOFA score decreased by more than 50% during the day following the withdrawal of noradrenaline (i.e. a subgroup of patients with a rapid improvement of the clinical course after the resolution of septic shock).

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Conditions

The condition(s) this trial relates to.

infectious disease with sepsis inflammatory disease multiple organ dysfunction syndrome Sepsis toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inflammatory response Multiorgan failure Sepsis Septic shock

Contacts and locations

Locations

  • University Hospital Ostrava

    Ostrava, Moravian-Silesian Region, 708 52, Czechia

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