New lung monitoring technique aims to reduce surgery complications
NCT ID NCT06446544
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether using a special ventilator monitor to track lung volume during one-lung surgery, combined with lung-opening maneuvers, can prevent lung collapse after surgery. 44 adults having lung surgery will be randomly assigned to either standard care or the monitoring plus maneuvers. The goal is to see if this approach reduces post-surgery lung problems.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- alveolar recruitment maneuvers guided by VPFE monitoring
- What this could lead to
- If successful, this could lead to a standard way to prevent lung collapse during one-lung surgery, reducing complications like pneumonia.
- What could go wrong
- This is a small, early-stage study with only 44 participants, so results may not apply to all patients. The intervention is a procedure, not a drug, and benefits may be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 44 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Jul 2026
An estimate. Start dates often move.
- Expected to finish
-
Aug 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 75 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
* Adult patient aged 18 to 75 years inclusive * Patient requiring lobectomy or segmentectomy by video or robot-thoracoscopy * Patient having read and understood the information letter and signed the consent form * Patient affiliated to a social security system * Women : * Of childbearing age (defined by the CTFG as a fertile woman, after menarche and until menopause, except in cases of permanent sterility (including hysterectomy, bilateral salpingectomy or bilateral oophorectomy)) * using effective contraception according to the WHO (combined hormonal contraception (containing estrogens and progestins), progestin-only contraception, intrauterine device (IUD), male or female condoms) for at least 4 weeks before inclusion and during the study And, * Presenting a negative urine pregnancy test at inclusion; * Menopause: menopause according to the CTFG is defined as the absence of periods for 12 months without any other medical cause. An elevated follicle-stimulating hormone (FSH) level in the postmenopausal interval can be used to confirm a postmenopausal state in women who are not using hormonal contraception or hormone replacement therapy. However, in the absence of 12 months of amenorrhea, a single FSH measurement is insufficient. Exclusion Criteria: * Patients aged 76 and over * COPD patients (Gold stage 3 or 4 of the 2023 Gold classification) * Patients with a history of ischemic coronary artery disease * Patients with a history of pulmonary emphysema bubbles on the ventilated lung * Tracheostomized patient * Obese patients (\>30 kg/m²) * Patients with a history of pulmonary resection * ASA patients ≥4 * Patient benefiting from a pre-operative rehabilitation protocol with physiotherapy * Pregnant or parturient or breastfeeding woman or proven absence of contraception * Person deprived of liberty by an administrative or judicial decision or person placed under judicial protection/under guardianship or curatorship * History of illness or psychological or sensory abnormality likely to prevent the subject from fully understanding the conditions required for participation in the protocol or preventing them from giving informed consent * Patient refusing to give consent.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Lung injury are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
CHU de ROUEN
Rouen, 76031, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Breathing rhythm may reveal hidden risks after lung surgery
- Can safer lung scans replace CT in infants? a study puts three methods to the test
- Which anesthesia is safer for septic lungs? new trial aims to find out
- Infant lung injury after bypass: scientists probe immune cell role
- Could a simple gas reduce lung damage in ventilator patients?
- Simple breath change could boost COPD inhaler power