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Mobile CT vans aim to detect lung cancer in smokers as young as 40

NCT ID NCT04577599

Diagnosis Sponsor: Wake Forest University Health Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This study uses mobile low-dose CT scans to screen for lung cancer in people aged 40-54 who have a heavy smoking history (30 pack-years or more). Participants in North and South Carolina will get up to three scans over time. The goal is to see if screening younger high-risk smokers can catch lung cancer at an earlier, more treatable stage.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mobile low-dose CT scan
What this could lead to
If successful, this could expand lung cancer screening to younger high-risk smokers, catching cancer earlier and saving more lives.
What could go wrong
This is an observational screening study, not a treatment trial. It may not prove that earlier detection improves survival in this age group, and false positives could cause unnecessary stress or procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 1,160 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2021

Expected to finish

Oct 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 54 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subject must meet all the following applicable inclusion criteria to participate in this study: 1. Written informed consent and HIPAA authorization for release of personal health information. NOTE: HIPAA authorization may be included in the informed consent or obtained separately. 2. Age 40-54 years at the time of consent. 3. A positive smoking history of greater/equal to 30 pack years and they are either currently smoking or have quit within the last 15 years. 4. Ability to read and understand the English and/or Spanish language. 5. Ability to understand and comply with study procedures for the entire length of the study. Exclusion Criteria: * Subjects meeting any of the criteria below may not participate in the study: 1. Known diagnosis of lung cancer in the past 5 years. 2. Any known contraindication to having a low-dose CT Scan. 3. Known pregnancy.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung cancer Lung neoplasms

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Levine Cancer Institute

    RECRUITING

    Charlotte, North Carolina, 28204, United States

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