Gene variants may raise lung cancer risk in Never-Smokers
NCT ID NCT07273279
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will analyze genetic data from 100,000 people to see if variations in aldehyde-metabolizing genes (ADH1B and ALDH family) are linked to lung cancer risk, especially in people who have never smoked. The goal is to understand how these genes might influence the development of lung cancer and its subtypes. No treatment is being tested; this is purely an observational genetic study.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help identify people with higher genetic risk for lung cancer, potentially leading to better screening or prevention strategies.
- What could go wrong
- This is an observational study that only looks at genetic associations, not a treatment trial. It may not find clear links, and results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 100,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Jan 2026
An estimate. Start dates often move.
- Expected to finish
-
Dec 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Lung cancer status determined by pathology-confirmed diagnosis at the time of case identification
- Ages
-
18 to 99 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Incident lung cancer cases confirmed by pathology and healthy adult over age of 18 years. Exclusion Criteria: * Individuals with incomplete data will not be included as study participants.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Condition/disease are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can AI tailor recovery instructions after lung cancer surgery?
- Can a new radiation machine cut breath holds for cancer patients?
- Software aims to steer bronchoscopes more precisely in lung cancer checks
- Gentle exercise may revive energy in lung cancer patients
- Laser and AI join forces to spot aggressive lung cancer
- Can a tiny camera help doctors diagnose lung nodules more accurately?