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Could less be more? new study aims to make transplants safer for blood cancer patients

NCT ID NCT03983850

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 38 times

Summary

This study looks at whether a lower dose of the drug cyclophosphamide, given after a stem cell transplant, can help control blood cancers like leukemia and lymphoma with fewer side effects. About 105 people aged 15-65 with high-risk blood cancers will receive a transplant from a half-matched relative. The goal is to reduce the risk of graft-versus-host disease, a common complication, while still controlling the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

The condition(s) this trial relates to.

graft versus host disease hematopoietic and lymphoid system neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.