Could less be more? new study aims to make transplants safer for blood cancer patients

NCT ID NCT03983850

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 27 times

Summary

This study looks at whether a lower dose of the drug cyclophosphamide, given after a stem cell transplant, can prevent serious side effects like graft-versus-host disease (GVHD) while still controlling blood cancers. About 105 people aged 15-65 with leukemia, lymphoma, or multiple myeloma will receive the lower dose, and researchers will monitor their recovery and side effects for up to 5 years. The goal is to make transplants safer and more effective.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.