Could less be more? new study aims to make transplants safer for blood cancer patients

NCT ID NCT03983850

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 38 times

Summary

This study looks at whether a lower dose of the drug cyclophosphamide, given after a stem cell transplant, can help control blood cancers like leukemia and lymphoma with fewer side effects. About 105 people aged 15-65 with high-risk blood cancers will receive a transplant from a half-matched relative. The goal is to reduce the risk of graft-versus-host disease, a common complication, while still controlling the cancer.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.