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Which anesthetic causes fewer sore throats after gallbladder surgery?

NCT ID NCT07440758

Symptom relief Sponsor: Kayseri City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 26, 2026 · Updated 4 times

Summary

This study looks at 70 adults having gallbladder removal surgery to see if one type of low-flow anesthesia (sevoflurane or desflurane) causes less sore throat afterward. Participants will be randomly assigned to one of the two anesthetics. The goal is to find which option leads to fewer throat problems and better recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Mar 2026

Finished

Jul 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status I-II * Aged between 18 and 65 years * Patients who provide written informed consent to participate in the study Exclusion Criteria: * Patients with a recent history of upper respiratory tract infection * Patients with a recent history of sore throat * Patients with chronic cough * Patients with a history of previous neck or tracheal surgery * Patients with predictors of difficult intubation * Patients with a history of difficult intubation * Obese patients (BMI \> 35 kg/m²) * Patients with chronic respiratory diseases (asthma, COPD) * Pregnancy * Use of dexamethasone * Patients with hepatic impairment * Patients with allergy to paracetamol, tramadol, granisetron, dexamethasone, or metoclopramide * Patients with known allergy to halogenated anesthetic agents * Patients with a history of malignant hyperthermia * Patients with mental disorders or those unable to provide reliable assessment

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Conditions

The condition(s) this trial relates to.

Postoperative Complications Postoperative Nausea and Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Laparoscopic cholecystectomy Postoperative sore throat

Contacts and locations

Locations

  • Kayseri City Hospital

    Kayseri, Kocasinan, 38080, Turkey (Türkiye)

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