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Which nerve block eases gallbladder surgery pain better?

NCT ID NCT07751770

Symptom relief Sponsor: Saglik Bilimleri Universitesi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This trial compares two ultrasound-guided nerve blocks for pain relief after laparoscopic gallbladder removal. Adults having this surgery will receive one of two blocks—either the modified thoracoabdominal nerve block or the erector spinae plane block—before waking from anesthesia. The study measures pain intensity, opioid use, and side effects over the first 24 hours after surgery to see if one technique offers better pain control.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If one nerve block proves better, it could become the preferred method for managing pain after gallbladder surgery, reducing opioid use and speeding recovery.
What could go wrong
This is a small, early-stage comparison, so results may not apply to all patients. Nerve blocks carry risks like bleeding, infection, or nerve damage, though rare.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Feb 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 65 years * Scheduled to undergo elective laparoscopic cholecystectomy under general anesthesia * American Society of Anesthesiologists physical status I to III * Body mass index below 35 kg/m² * International Normalized Ratio and platelet count within the institutional reference ranges * Liver and renal function test results within the institutional reference ranges * Provision of written informed consent Exclusion Criteria: * Bleeding diathesis * Known allergy to local anesthetics * Infection or inflammation at the planned block application site * Gallbladder perforation * Known neurological disease * American Society of Anesthesiologists physical status IV or higher * Long-term medication use for chronic pain * Advanced liver or renal failure * Previous abdominal surgery or abdominal trauma * Use of any opioid medication within 24 hours before surgery * Pregnancy * Refusal to participate * Intraoperative conversion from laparoscopic to open surgery

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Laparoscopic cholecystectomy Postoperative pain

Contacts and locations

Locations

  • Istanbul Provincial Directorate of Health Sultan 2.Abdul Hamid Khan Educational and Research Hospital

    Istanbul, 34000, Turkey (Türkiye)

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