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Common drug tested for hidden power against debilitating autoimmune symptoms

NCT ID NCT03482479

Summary

This study tested whether a very low dose of an existing medication (naltrexone) could improve daily life for people with several types of vasculitis, a group of autoimmune diseases that cause blood vessel inflammation. The trial involved 60 adults whose disease was stable but who still struggled with poor physical health, fatigue, or pain. Participants took either the low-dose drug or a placebo for six-week periods to see if their self-reported quality of life improved.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • St. Joseph's Healthcare

    Hamilton, Ontario, Canada

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15260, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.