Alcoholism drug repurposed to fight pain and fatigue in rare autoimmune diseases

NCT ID NCT03482479

Summary

This study tested whether a very low dose of an existing drug, naltrexone, could improve daily life for people with vasculitis, a group of rare autoimmune diseases that cause blood vessel inflammation. Sixty patients whose disease was stable but who still struggled with poor physical health, fatigue, or pain took either the drug or a placebo for 6-week periods. The main goal was to see if the drug helped patients feel better and function better in their daily lives compared to the placebo.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • St. Joseph's Healthcare

    Hamilton, Ontario, Canada

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15260, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.