Magnesium may ease pain after back surgery, small study suggests
NCT ID NCT07418580
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether giving a low dose of magnesium sulfate during lower back surgery can help reduce pain afterward. Sixty adults having lumbar spine surgery received either magnesium or a placebo. The goal was to see if magnesium could lower pain scores and the need for stronger painkillers like opioids.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Apr 2021
- Finished
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Nov 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * aged 18 years and older, * ASA (American Society of Anesthesiologists) physical status I-II, * awaiting to undergo lumbar spinal surgery under general anesthesia. Exclusion Criteria: * the presence of cardiac conduction disorders and/or cardiac comorbidities * use of Ca channel blockers, * hepatic/renal failure and allergy to Mg.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sisli etfal research and training hospital
Istanbul, 34371, Turkey (Türkiye)
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