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Fasting for five days: scientists track what happens when you stop eating

NCT ID NCT07155993

Knowledge-focused Sponsor: Buchinger Wilhelmi Development & Holding GmbH Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study follows 300 adults with diabetes, prediabetes, or overweight who fast for at least five days at a clinic. Researchers track changes in weight, blood sugar, and well-being during the fast and for three months after, using questionnaires, continuous glucose monitors, and home blood tests. The goal is to understand how the body adapts to prolonged fasting and the return to normal eating.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
medically supervised long-term fasting (5+ days) followed by structured food reintroduction
What this could lead to
If successful, this study could provide practical guidance on how fasting affects metabolism and weight, helping people use fasting safely for health benefits.
What could go wrong
This is an observational study, not a treatment trial. Results may not apply to everyone, and fasting can cause side effects like dizziness or nutrient imbalances. The study relies on self-reported data, which can be less reliable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2024

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients of the Buchinger Wilhelmi clinic in Überlingen

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men and women * Fasting for 5+ days at the Buchinger Wilhelmi clinic in Überlingen or Marbella * Age: 18-90 years old * Signed informed consent Exclusion Criteria: * Not able to sign the informed consent * Diagnosed with cachexia, anorexia nervosa, advanced kidney, liver or cerebrovascular insufficiency. * Chronic manifest psychical and psychiatric diseases * Participation in another study * Pregnancy or breastfeeding

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Fasting glucose intolerance Overweight prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabetes (DM) Overweight (bmi > 25) Pre diabetes

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Buchinger Wilhelmi Klinik

    Überlingen, Baden-Wurttemberg, 88662, Germany

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