Personalized immune monitoring could transform liver transplant care
NCT ID NCT06063213
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing a new method to monitor the immune system after a liver transplant. The goal is to see if a personalized approach can help doctors adjust immunosuppression drugs more accurately, reducing the risk of rejection or infection. Forty adult liver transplant recipients will be followed for six months to track episodes of rejection and infection.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Phenotypic personalized medicine (PPM) protocol
- What this could lead to
- If successful, this could lead to a more personalized approach to managing immunosuppression after liver transplant, potentially reducing rejection and infection.
- What could go wrong
- This is a small, early-stage study with only 40 participants, so results may not apply to all transplant patients. The approach is still being tested and may not improve outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Dec 2023
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients that are simultaneous Liver Kidney Transplant recipients that are one month post transplant. Patients that are Liver Transplant recipients that are one month post transplant.
- Ages
-
18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * At least 18 years of age * At least one-month post-transplant * Recipient of a liver transplant alone or a simultaneous liver-kidney transplant Exclusion Criteria: * Unwilling to provide informed consent * Recipient of a previous bone marrow or stem cell transplant * Pregnant * Unlikely to be able to comply with the study requirements, as determined by the PI
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Florida
Gainesville, Florida, 32608, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- 10,000 transplant patients to be tracked for hidden heart risks
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