Nanoparticle inhaler could tame lung transplant rejection
NCT ID NCT07234760
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new way to deliver the drug everolimus directly to the lungs using tiny particles called liposomes. The goal was to treat chronic lung rejection (bronchiolitis obliterans syndrome) after a lung transplant. Researchers used human lung tissue and cells in the lab to see if this inhaled approach could reduce side effects and target the diseased cells more effectively.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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19 people
The number who actually took part.
- Started
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Mar 2022
- Finished
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Jul 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
BOS affected patients
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- BOS/subjected to TX patients
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fondazione IRCCS Policlinico San Matteo
Pavia, Lombardy, 27100, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.