Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Numbing shot may cut opioid need after leg surgery, but trial stalls

NCT ID NCT05992896

Symptom relief Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether injecting a long-acting numbing drug (liposomal bupivacaine) during leg artery surgery could lower the amount of narcotics patients need during and after the procedure. The trial planned to enroll adults having elective lower extremity revascularization, but it was terminated early after only 3 participants. Because of the small size, no meaningful conclusions can be drawn about the drug's effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
liposomal bupivacaine (a long-acting numbing medicine)
What this could lead to
If it worked, this approach could help patients use fewer narcotics after leg surgery, potentially reducing side effects and addiction risk.
What could go wrong
The trial was terminated early with only 3 participants, so no reliable conclusions can be drawn. The results may not apply to a broader population.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

3 people

The number who actually took part.

Started

Sep 2023

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Those who present for elective lower extremity revascularization. Exclusion Criteria: * Non-English speaking. * Chronic pain. * On opioids greater than 1 weeks. * Allergy to local anesthetics. * Use of spinal or epidural for surgery. * Lack of patient cooperation. * Contraindication to regional anesthesia. * Vulnerable individuals. * Urgent/emergent surgeries * Known to be pregnant or able to become pregnant

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Peripheral arterial disease are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Narcotic-Related Disorders peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Peripheral arterial disease

Contacts and locations

Locations

  • Mayo Clinic Health System - Eau Claire

    Eau Claire, Wisconsin, 54703, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.