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Can a common antibiotic beat syphilis?

NCT ID NCT05548426

First seen Mar 16, 2026 · Last updated Jun 11, 2026 · Updated 17 times

Summary

This study tests whether the antibiotic linezolid can effectively treat early syphilis in 24 adults. Participants have primary, secondary, or early latent syphilis, and some also have well-controlled HIV. The main goal is to see if linezolid reduces syphilis infection markers in the blood within 6 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Howard Brown Health

    Chicago, Illinois, 60613, United States

  • Open Arms HealthCare Center

    Jackson, Mississippi, 39216, United States

  • Open Door Health

    Providence, Rhode Island, 02907, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, 39216, United States

  • Wake Forest Baptist Health

    Greensboro, North Carolina, 27405, United States

Conditions

The condition(s) this trial relates to.

syphilis Treponema infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.