Can a lifestyle program beat a pill for Post-Diabetes weight loss?
NCT ID NCT06948825
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 37 times
Summary
This study tests whether a 6-month lifestyle program (diet, exercise, coaching) or the drug metformin is better for weight loss in mothers who recently had gestational diabetes. Sixty women who gave birth in the last year will join. Participants track their activity and weight, attend online group sessions, and may get extra support like free groceries. The goal is to find the most effective way to help these mothers lose weight and improve their health.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Milken Institute School of Public Health - The George Washington University
RECRUITINGWashington D.C., District of Columbia, 20052, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Metformin (a diabetes medication) and a lifestyle program (diet, exercise, and coaching)
What this could lead to
If it works, this could show that a lifestyle program is as good as or better than metformin for helping mothers lose weight after gestational diabetes, pointing toward a non-drug option.
What could go wrong
This is a small, early-phase study with only 60 people. Results may not apply to everyone, and weight loss can be hard to maintain. Metformin can cause stomach upset.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.