New fingerprick test and antibiotic aim to stop leprosy before it starts
NCT ID NCT06222372
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study in Bangladesh tests whether giving a single dose of the antibiotic rifampin to people who live with or near leprosy patients can prevent infection. Researchers will use a new fingerprick blood test to measure infection markers before and after treatment. The goal is to find an easy way to stop leprosy from spreading.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Rifampin (antibiotic)
- What this could lead to
- If successful, this could provide a simple way to identify and treat people at risk of leprosy before they develop the disease, helping to stop its spread.
- What could go wrong
- This is an early-stage study focused on measuring infection markers, not preventing disease directly. The test and treatment may not work as hoped in real-world settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2020
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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5 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria patients: \- newly diagnosed multibacillary leprosy patients (BI 1-6) Inclusion Criteria contacts of MB leprosy patients: * living in the same house (household members) * living in a house on the same compound * sharing the same kitchen * direct neighbors (first neighbors) * willing to participate * provide informed consent Exclusion Criteria patients: * refusal of examination of their contacts * suffering from the pure neural form of leprosy * residing only temporarily in the study area * PB leprosy patients Exclusion Criteria contacts: * diagnosed as leprosy patients during contact examination * living less than 100 m away from a patient already included in the study * first and second degree relatives of a patient already included in the study * refusal informed consent * pregnancy * tuberculosis or leprosy treatment * below 5 years of age * known to suffer from liver disease or jaundice * residing temporarily in the study area
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The Leprosy Mission International - Bangladesh
RECRUITINGNilphamari, 5300, Bangladesh
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- Umbilical cord injection shows promise for stubborn leprosy ulcers
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