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New registry tracks stroke prevention without blood thinners

NCT ID NCT05565209

First seen Jan 19, 2026 · Last updated Jun 23, 2026 · Updated 23 times

Summary

This study follows 250 atrial fibrillation patients who received a left atrial appendage closure device to prevent strokes. The procedure blocks a small pouch in the heart where clots often form, allowing patients to avoid long-term blood thinners. Researchers will track how many patients have strokes or other clots over five years to see how well the procedure works in the long run.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Assistance Publique Hôpitaux de Paris - CHU HENRI MONDOR

    RECRUITING

    Créteil, 94010, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Left atrial appendage closure device

What this could lead to

If successful, this study could confirm that left atrial appendage closure is a safe and effective long-term alternative to blood thinners for preventing strokes in atrial fibrillation patients.

What could go wrong

This is an observational registry, not a controlled trial, so results may not prove cause and effect. Long-term data collection may have missing or incomplete records.

Conditions

The condition(s) this trial relates to.

atrial fibrillation Hemorrhage stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.