New study to settle: laser or PRP for acne scars?
NCT ID NCT07189923
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will compare two common treatments for acne scars: ablative fractional CO2 laser and platelet-rich plasma (PRP) combined with microneedling. 116 adults with moderate to severe atrophic acne scars will receive each treatment on opposite sides of their face. The goal is to see which method improves scars more effectively and safely.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Ablative fractional CO2 laser and platelet-rich plasma (PRP) with microneedling
- What this could lead to
- If this works, it could show which treatment is better for reducing acne scars, helping doctors choose the most effective option.
- What could go wrong
- This is a small, early-stage study that hasn't started yet. Results may not apply to everyone, and both treatments have risks like redness, swelling, or scarring.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 116 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients (age \>18 years) * Both male and female sex * Patients with grade 2 to grade 4 acne scars, classified on the basis of Goodman's Qualitative classification. * Patient with equal Goodman's Qualitative scores on both halves of the face. * No active acne lesions. * Patients with atrophic scars only. Exclusion Criteria: * Positive history of keloidal tendency. * Positive history of bleeding or platelet disorder. * Positive history of major surgery in past 6 months. * Presence of any acute infection on face like, herpes, folliculitis. * Patients of HIV, HBsAg, or any chronic illness. * Pregnancy
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Dhala Medical College
Dhaka, Bangladesh
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