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New laser combo could make toothache treatment less painful for kids

NCT ID NCT07290049

Symptom relief Sponsor: University of Fujairah Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times

Summary

This study tests whether using a gentle laser along with a special dental cement can reduce pain after a pulpotomy, a procedure that saves a tooth with a severe nerve infection. About 46 children and young adults aged 9 to 14 with a painful lower molar will be randomly assigned to get either the cement alone or the cement plus laser. The main goal is to see if the laser helps lower pain after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Calcium silicate cement (EndoCem MTA) and Er,Cr:YSGG laser
What this could lead to
If it works, this could offer a less painful way to treat severe toothaches in children, possibly avoiding root canals.
What could go wrong
This is a small early study with only 46 people, so results may not apply to everyone. The laser might not reduce pain more than the cement alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

46 people

The number who actually took part.

Started

Apr 2025

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

9 to 14 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients between 9 and 14 years of age * Presence of a two-rooted permanent mandibular molar * Clinical diagnosis of symptomatic irreversible pulpitis in the study tooth * Study tooth considered restorable with a definitive restoration * Study tooth is periodontally healthy, with no mobility and no tenderness to percussion or palpation * Participant and/or parent/legal guardian is able and willing to provide written informed consent Exclusion Criteria: * Teeth with immature root apices * Teeth that are non-restorable because of extensive caries or structural damage * Inability to achieve hemostasis within 10 minutes after coronal pulp removal * Participants with significant systemic medical conditions that may affect dental treatment or healing * Teeth diagnosed with pulpal necrosis * Inability or unwillingness of the participant and/or parent/legal guardian to provide informed consent * Individuals belonging to vulnerable populations, as defined by the institutional ethics committee

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Symptomatic irreversible pulpitis Symptomatic irreversible pulpitis (SIP)

Contacts and locations

Locations

  • Dental Clinic, College of Dentistry, Fujairah University

    Fujairah, Emirate of Fujairah, 2202, United Arab Emirates

More trials for these conditions

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