Which nerve block wins for knee surgery pain?
NCT ID NCT07082374
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested three different nerve blocks to see which provides the best pain relief after total knee replacement. Sixty adults having knee surgery under general anesthesia received one of the blocks. The main goal was to measure how long it took before they needed extra pain medicine. The results help doctors choose the best option for managing post-surgery pain.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Jul 2025
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age from 18 to 75 years. * Both sexes. * American Society of Anesthesiology (ASA) physical status I-II. * Undergoing total knee arthroplasty (TKA) under general anesthesia. Exclusion Criteria: * Severe valgus deformity. * Acute/chronic kidney disease. * Neurological deficit. * Cognitive dysfunction. * Local infection at the site of injection. * Coagulopathy. * Hypersensitivity and/or allergies to local anesthetic (LA) or any of the study medications. * Chronic opioid consumption (daily or almost daily use of opioids for \> three months). * Operative limb neuropathy.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tanta University
Tanta, El-Gharbia, 31527, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Prepping the knee before surgery: a new approach to better recovery