Knee surgery pain showdown: which block wins?
NCT ID NCT05561881
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared two types of nerve blocks—genicular nerve block and IPACK block—for pain relief after knee arthroscopy. Fifty adults aged 20-60 were enrolled. The main goal was to see which block provides better pain control in the first 24 hours after surgery. Both blocks use local anesthetic to numb the knee area.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- local anesthetic
- What this could lead to
- If one block works better, it could improve pain control and reduce opioid use after knee surgery.
- What could go wrong
- This is a small, completed study with only 50 participants, so results may not apply to everyone. Both blocks are standard procedures, so no major new risks are expected.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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50 people
The number who actually took part.
- Started
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Dec 2022
- Finished
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Mar 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * age 20\_60 years * American Society of anthologist class I-III * BMI18\_35 kg/m2 * scheduled for primary unilateral knee arthroscopic surgery Exclusion Criteria: * known allergy to local anesthesia * contraindication to local anesthesia injection (e.g., infection at the site of injection * contraindication to spinal anesthesia (e.g., coagulopathy) * patients with preexisting motor or sensory deficit in lower extremities * insulin or non-insulin-dependent diabetes mellitus * systemic corticosteroids use within 30 days * history of arrhythmia or seizures * severe renal insufficiency * patient refusal
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Assiut University
Asyut, Asyut Governorate, Egypt
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