Adding hip or ankle moves to knee exercises eases pain in women with Runner's knee
NCT ID NCT07210060
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding hip or ankle exercises to standard knee strengthening could help women with patellofemoral pain syndrome (anterior knee pain). Forty-five female recreational athletes aged 20-40 completed an 8-week telehealth-supervised program. Both the hip-plus-knee and ankle-plus-knee exercise groups showed similar improvements in pain and movement control compared to a stretching-only group.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- exercise therapy (knee strengthening plus hip or ankle exercises)
- What this could lead to
- If confirmed, this could point toward more effective exercise programs for women with anterior knee pain, reducing pain and improving function without surgery or drugs.
- What could go wrong
- This is a small, completed trial with only 45 participants, all female recreational athletes. Results may not apply to men, non-athletes, or people with different types of knee pain. The study did not test long-term outcomes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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45 people
The number who actually took part.
- Started
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Jul 2023
- Finished
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Jul 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Female recreational athletes aged 20-40 years who engage in regular exercise 2. Experiencing pain in the anterior or surrounding patella during at least two or more of the following activities: walking, running, jumping, kneeling, squatting, climbing stairs, or prolonged sitting 3. A pain index of 3 or higher on the Numeric Pain Rating Scale (NPRS) and symptoms persisting for at least 3 months 4. Knee pain unrelated to trauma. Exclusion Criteria: 1. Inability to operate a smartphone or computer 2. History of fractures or surgeries involving the hip, knee, ankle, or foot 3. History of meniscus, knee ligament injuries, or ankle sprains within the last six months 4. Knee ligament laxity, inflammation, swelling, patellar dislocation, or subluxation 5. Cognitive impairment or inability to follow simple instructions 6. History of cardiovascular or neurological disorders 7. Advised by a physician to avoid exercise. Use of over-the-counter pain medication was not an exclusion criterion.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Nai-Jen Chang
Tainan, Kaohsiung City, 807, Taiwan
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