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Which procedure wins for kidney stones in oddly shaped kidneys?

NCT ID NCT05240170

Disease control Sponsor: Al-Azhar University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial compares two ways to treat kidney stones in people whose kidneys are shaped or positioned abnormally from birth. One method, retrograde intrarenal surgery (RIRS), uses a thin scope passed through the urinary tract to break up stones with a laser. The other, shockwave lithotripsy (SWL), sends shock waves from outside the body to shatter stones. The study will see which approach clears more stones completely, with fewer complications and less need for repeat treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Two procedures are compared: retrograde intrarenal surgery (RIRS), using a flexible scope and laser to break up stones, and extracorporeal shockwave lithotripsy (SWL), which uses shock waves from outside the body to fragment stones.
What this could lead to
If RIRS proves more effective, it could become the preferred treatment for kidney stones in people with congenital kidney anomalies, improving stone clearance and reducing the need for repeat procedures.
What could go wrong
This is a single-center study, and results may not apply to all patients. RIRS is more invasive and carries risks like bleeding or infection, while SWL may be less effective for certain stone types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

160 people

The number who actually took part.

Started

Mar 2022

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * The study will include patients with renal stones up to 20 mm in size in a kidney with rotation or position anomalies. Exclusion Criteria: * Pregnant women. * Uncorrectable coagulation disorders. * Urinary tract obstruction distal to the stone. * Active infection. * Stone in a calyceal diverticulum

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Renal anomaly Renal calculi

Contacts and locations

Locations

  • Urology Department, Al-Azhar University Hospital

    Cairo, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.