Could a simple breathing change make kidney stone surgery easier?
NCT ID NCT07643324
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two breathing machine settings during kidney stone surgery to see which one gives surgeons a clearer, steadier view inside the kidney. Sixty adults having elective surgery will be randomly assigned to either normal or low tidal volume ventilation. The goal is to reduce kidney movement caused by the breathing machine, which may help the surgeon break up stones more efficiently.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- low tidal volume ventilation (a breathing machine setting during surgery)
- What this could lead to
- If it works, this could make kidney stone surgery smoother and faster by reducing kidney movement during the procedure.
- What could go wrong
- This is a small, early-stage trial with only 60 participants, so results may not apply to all patients. The benefit is about surgical convenience, not a cure or major health improvement.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients aged 18 years or older * Patients scheduled for elective retrograde intrarenal surgery under general anesthesia * ASA physical status I-III * Patients who are able to read and understand the informed consent form * Patients who provide written informed consent Exclusion Criteria: * Patients younger than 18 years * Pregnancy * Emergency surgery * Severe chronic obstructive pulmonary disease, severe restrictive pulmonary disease, or preoperative hypercapnia * Severe uncontrolled cardiovascular disease * Active urinary tract infection, sepsis, or untreated infectious focus * Cases in whom the standardized ventilation protocol is difficult to apply because of morbid obesity * Patients scheduled for an additional major urological procedure in the same session * Cases in which an intraoperative video recording of sufficient quality cannot be obtained * Patients in whom the study protocol cannot be safely continued according to the investigator's clinical judgment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hitit university
RECRUITINGÇorum, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Stent before surgery: a new test for kidney stone treatment
- Which procedure wins for kidney stones in oddly shaped kidneys?
- Holding breath during kidney stone surgery may speed up treatment
- Kidney stone showdown: shock waves vs. tiny surgery