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Could a simple breathing change make kidney stone surgery easier?

NCT ID NCT07643324

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two breathing machine settings during kidney stone surgery to see which one gives surgeons a clearer, steadier view inside the kidney. Sixty adults having elective surgery will be randomly assigned to either normal or low tidal volume ventilation. The goal is to reduce kidney movement caused by the breathing machine, which may help the surgeon break up stones more efficiently.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
low tidal volume ventilation (a breathing machine setting during surgery)
What this could lead to
If it works, this could make kidney stone surgery smoother and faster by reducing kidney movement during the procedure.
What could go wrong
This is a small, early-stage trial with only 60 participants, so results may not apply to all patients. The benefit is about surgical convenience, not a cure or major health improvement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18 years or older * Patients scheduled for elective retrograde intrarenal surgery under general anesthesia * ASA physical status I-III * Patients who are able to read and understand the informed consent form * Patients who provide written informed consent Exclusion Criteria: * Patients younger than 18 years * Pregnancy * Emergency surgery * Severe chronic obstructive pulmonary disease, severe restrictive pulmonary disease, or preoperative hypercapnia * Severe uncontrolled cardiovascular disease * Active urinary tract infection, sepsis, or untreated infectious focus * Cases in whom the standardized ventilation protocol is difficult to apply because of morbid obesity * Patients scheduled for an additional major urological procedure in the same session * Cases in which an intraoperative video recording of sufficient quality cannot be obtained * Patients in whom the study protocol cannot be safely continued according to the investigator's clinical judgment

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hitit university

    RECRUITING

    Çorum, Turkey (Türkiye)

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