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Brain scans reveal Ketamine's secret weapon against depression

NCT ID NCT05915013

First seen May 09, 2026 · Last updated May 23, 2026 · Updated 3 times

Summary

This study looks at how ketamine helps people with hard-to-treat depression and PTSD. Researchers will give participants ketamine with or without another drug called perampanel to see how it changes brain activity. The goal is to understand the brain processes behind ketamine's fast-acting antidepressant effects. About 50 adults with treatment-resistant depression will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06511, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.