Could a single dose of ketamine during heart surgery stop Long-Term pain?
NCT ID NCT07490457
First seen Apr 15, 2026 · Last updated Jun 23, 2026 · Updated 15 times
Summary
This study will test whether giving a single dose of ketamine during open-heart surgery can reduce chronic pain that often lingers for months after the operation. Researchers will compare 100 adults who receive either ketamine or a placebo during surgery, then track their pain levels and painkiller use for up to 6 months. If successful, this simple addition to anesthesia could improve recovery and reduce reliance on opioids.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Bursa City Hospital,
Bursa, nilüfer, Turkey (Türkiye)
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketamine
What this could lead to
If it works, this could point toward a simple way to prevent long-term pain after open-heart surgery and reduce the need for strong painkillers.
What could go wrong
This is a small, early-stage trial (100 people) that hasn't started yet. The results may not apply to all heart surgery patients, and ketamine can cause side effects like confusion or hallucinations.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.