Ketamine infusion during sedation: a new hope for chronic pain and depression?
NCT ID NCT06317636
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 35 times
Summary
This study tests whether a single dose of ketamine, given while patients are sedated, can help with chronic pain and depression. Forty adults with both conditions will receive either ketamine or a placebo (saline) during propofol sedation. Researchers will track pain and depression levels over several weeks to see if ketamine works better than placebo.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DEPRESSION are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
-
Stanford University
Stanford, California, 94305, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketamine
What this could lead to
If it works, this could show that ketamine given during sedation helps reduce chronic pain and depression symptoms.
What could go wrong
This is a small, early-phase trial with only 40 participants. It may not show a clear benefit over placebo, and results may not apply to everyone.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.