Gene therapy eye drops aim to heal corneas in rare disease
NCT ID NCT06999733
First seen Feb 28, 2026 · Last updated May 20, 2026 · Updated 14 times
Summary
This study tests an experimental eye drop called KB801 for people with stage 2 or 3 neurotrophic keratitis, a condition where the cornea loses feeling and develops persistent sores. The drop delivers a gene that produces nerve growth factor to help heal the cornea. About 60 adults will receive either KB801 or a placebo to check safety and whether the sores heal completely by week 8.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Azul Vision - California Eye Specialists Medical Group Inc.
RECRUITINGPasadena, California, 91107, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Metropolitan Eye Research and Surgery Institute
RECRUITINGPalisades Park, New Jersey, 07650, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Midwest Cornea Associates
RECRUITINGCarmel, Indiana, 46290, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Minnesota Eye Consultants
RECRUITINGMinnetonka, Minnesota, 55305, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St. Louis Eye Institute
RECRUITINGTown and Country, Missouri, 63017, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-••••
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UC Irvine Alpha Clinic
NOT_YET_RECRUITINGIrvine, California, 92617, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UPMC Vision Institute
NOT_YET_RECRUITINGPittsburgh, Pennsylvania, 15219, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vance Thompson Vision
RECRUITINGAlexandria, Minnesota, 56308, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vance Thompson Vision
RECRUITINGWest Fargo, North Dakota, 58078, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.