Gene therapy eyedrop offers hope for rare corneal blindness

NCT ID NCT06999733

First seen Feb 28, 2026 · Last updated May 16, 2026 · Updated 13 times

Summary

This study tests a new gene therapy called KB801 for people with stage 2 or 3 neurotrophic keratitis, a rare eye disease where the cornea loses feeling and can develop sores that won't heal. The treatment is an eyedrop that delivers a protein to help the cornea repair itself. About 60 adults will receive either KB801 or a placebo to see if it safely heals the cornea.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azul Vision - California Eye Specialists Medical Group Inc.

    RECRUITING

    Pasadena, California, 91107, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Metropolitan Eye Research and Surgery Institute

    RECRUITING

    Palisades Park, New Jersey, 07650, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Midwest Cornea Associates

    RECRUITING

    Carmel, Indiana, 46290, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Minnesota Eye Consultants

    RECRUITING

    Minnetonka, Minnesota, 55305, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Louis Eye Institute

    RECRUITING

    Town and Country, Missouri, 63017, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-••••

  • UC Irvine Alpha Clinic

    NOT_YET_RECRUITING

    Irvine, California, 92617, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UPMC Vision Institute

    NOT_YET_RECRUITING

    Pittsburgh, Pennsylvania, 15219, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vance Thompson Vision

    RECRUITING

    Alexandria, Minnesota, 56308, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vance Thompson Vision

    RECRUITING

    West Fargo, North Dakota, 58078, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.